Download e-book for kindle: Amyotrophic Lateral Sclerosis and the Frontotemporal by Michael J. Strong

By Michael J. Strong

ISBN-10: 0199590672

ISBN-13: 9780199590674

During the last ten years, there was an expanding reputation that syndromes of frontotemporal disorder (FTD) are a standard incidence in sufferers with amyotrophic lateral sclerosis (ALS). Such syndromes will be found in as many as 60% of sufferers with ALS. Conversely, the incidence of motor neuron disorder in sufferers with clinically natural frontotemporal dementia is more and more famous. this implies that to some degree there are overlapping syndromes during which either ALS and FTD take place in the related person.

This quantity summarizes the advances in our figuring out of those issues, in addition to the aptitude courting among the 2. Key subject matters contain advances in our skill to clinically describe the frontotemporal syndromes, preclinical detection, neuroimaging, and genetics. The exploding box of recent markers in neuropathology is tested, as is the function of recent genetic mutations in DNA/RNA delivery structures. This booklet is the basic reference textual content for this subject, and may be of curiosity to neurologists and neurological trainees with a medical or learn curiosity within the FTDs or ALS, neuropsychologists, neuropathologists, and researchers.

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Additional info for Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

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Le Forestier N, Maisonobe T, Piquard A, et al. (2001). Does primary lateral sclerosis exist? A study of 20 patients and a review of the literature. Brain, 124, 1989–1999. 40. Cedarbaum JM, Stambler N, Malta E, et al. (1999). The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci, 169, 13–21. 41. Van den Berg-Vos RM, Visser J, Kalmijn S, et al. (2009). A long-term prospective study of the natural course of sporadic adult-onset lower motor neuron syndromes.

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Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias by Michael J. Strong

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