By Valentin Fuster MD PhD, Eric J. Topol MD, Elizabeth G. Nabel MD
Written via the world’s most desirable specialists, this quantity offers accomplished insurance of present techniques to the prevention, analysis, and administration of atherothrombosis and its coronary and noncoronary problems. This version has been completely up to date, sharply concerned with medical info, and trimmed to at least one possible volume.
Coverage starts off with a evaluate of threat components and prevention, emphasizing lipid abnormalities, high blood pressure, smoking, diabetes, and weight problems. next sections research the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, power strong angina, and noncoronary atherothrombosis. medical shows, scientific administration, and the most recent interventional thoughts are included.
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Additional info for Atherothrombosis and coronary artery disease
After presenting cases with autopsy correlations, Obrastzow and Straschesko concluded that “the differential diagnosis of coronary thrombosis from angina pectoris is made by the presence of status anginosus with coronary thrombosis and its absence with isolated attacks of angina pectoris” (37,38). Although this article, published in German, attracted little attention, it was known to Chicago internist James Herrick, who eventually convinced the medical community that acute coronary thrombosis could be recognized during life (Fig.
Levine SA. Coronary thrombosis: its various clinical features. Baltimore: Williams & Wilkins, 1929. 42. Sones FM Jr, Shirey EK. Cine coronary arteriography. Mod Concepts Cardiovasc Dis 1962;31:735–738. 43. Fye WB. Ventricular fibrillation and defibrillation: historical perspectives. Circulation 1985;71:858–865. 44. Fye WB. Disorders of the heartbeat: a historical overview from antiquity to the mid-20th century. Am J Cardiol 1993;72:1055–1070. 45. Day HW. A cardiac resuscitation program. Lancet 1962;82:153–156.
Scottish medical student Thomas Lauder Brunton introduced amyl nitrite for the treatment of angina pectoris in 1867 (30) (Fig. 1–6). Brunton’s mentors at the University of Edinburgh had been experimenting with the substance and were impressed by the immediate and profound effects that followed its inhalation. Using a new instrument, the sphygmograph, they found that amyl nitrate predictably decreased the arterial tension in animals and humans. Brunton found that blood pressure increased and the pulse quickened during anginal attacks.
Atherothrombosis and coronary artery disease by Valentin Fuster MD PhD, Eric J. Topol MD, Elizabeth G. Nabel MD