Cardiovascular Hormone Systems: From Molecular Mechanisms to - download pdf or read online

By Michael Bader

ISBN-10: 3527319204

ISBN-13: 9783527319206

ISBN-10: 3527626239

ISBN-13: 9783527626236

Content material:
Chapter 1 Glucocorticoids and Mineralocorticoids (pages 1–37): Eilidh Craigie, John J. Mullins and Matthew A. Bailey
Chapter 2 intercourse Steroid Hormones (pages 39–64): Vera Regitz?Zagrosek, Eva Becher, Shokoufeh Mahmoodzadeh and Carola Schubert
Chapter three Angiotensins (pages 65–100): Robson Augusto Souza Dos Santos, Anderson Jose Ferreira and Ana Cristina Simoes e Silva
Chapter four Kinins (pages 101–123): Suzana Macedo de Oliveira, Kely de Picoli Souza, Michael Bader and Joao Bosco Pesquero
Chapter five Natriuretic Peptides (pages 125–141): Paula M. Bryan and Lincoln R. Potter
Chapter 6 Endothelins (pages 143–167): Gian Paolo Rossi and Teresa M. Seccia
Chapter 7 Adrenomedullin (pages 169–191): Istvan Szokodi and Heikki Ruskoaho
Chapter eight Apelin and Vasopressin (pages 193–208): Xavier Iturrioz, Annabelle Reaux?Le Goazigo, Francoise Moos and Catherine Llorens?Cortes
Chapter nine Serotonin (pages 209–231): Prof. Dr. Michael Bader
Chapter 10 Adrenaline and Noradrenaline (pages 233–250): Nadine Beetz and Lutz Hein
Chapter eleven Dopamine (pages 251–293): Pedro Gomes and Patriio Soares?da?silva
Chapter 12 Histamine (pages 295–314): Izabela Rozenberg, Felix C. Tanner and Thomas F. Luscher
Chapter thirteen Prostaglandins and Leukotrienes (pages 315–331): Katharina Lotzer and Andreas J. R. Habenicht
Chapter 14 Cytochrome P450?Dependent Eicosanoids (pages 333–372): Wolf?Hagen Schunck and Cosima Schmidt
Chapter 15 Nucleotides and the Purinergic process (pages 373–393): Vera Jankowski and Joachim Jankowski
Chapter sixteen Nitric Oxide (pages 395–406): Valerie B. Schini?Kerth and Paul M. Vanhoutte
Chapter 17 Acetylcholine (pages 407–424): Maria Claudia Irigoyen, Catarina S. Porto, Pedro Paulo Soares, Fernanda Consolin?Colombo and Antonio Claudio Nobrega

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Extra info for Cardiovascular Hormone Systems: From Molecular Mechanisms to Novel Therapeutics

Sample text

Expressing 11βHSD2 selectively in cardiomyoctes [102]. 7). Moreover, an MR antagonist rescued the cardiopathology, whereas a GR antagonist did not. These data indicate that (i) glucocorticoids normally occupy cardiac MR, but act as an antagonist rather than agonist, and (ii) that aldosterone activation of MR – only observed when 11βHSD2 prevents glucocorticoid occupancy – is detrimental to heart function. The data above are confusing and often conflicting, suggesting that MR blockade is both beneficial and damaging and that glucocorticoids can both activate and antagonize the MR.

A. J. (2006) Hypertension, kidney, and transgenics: a fresh perspective. Physiological Reviews, 86, 709–46. B. (1985) Analysis of longterm potassium regulation. Endocrine Reviews, 6, 24–44. W. E. (1976) Acute and chronic dose–response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. Circulation Research, 39, 788–97. K. A. (2000) Pituitary–adrenal axis regulation in CRH-deficient mice. Endocrine Research, 26, 1057–66. F. and Rivier, C. (1999) CRF type I receptor-deficient mice exhibit a pronounced pituitary– adrenal response to local inflammation.

W. A. (2007) Aliskiren for renin inhibition: a new class of antihypertensives. Annals of Pharmacotherapy, 41, 456–64. A. J. (2006) Hypertension, kidney, and transgenics: a fresh perspective. Physiological Reviews, 86, 709–46. B. (1985) Analysis of longterm potassium regulation. Endocrine Reviews, 6, 24–44. W. E. (1976) Acute and chronic dose–response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. Circulation Research, 39, 788–97. K. A. (2000) Pituitary–adrenal axis regulation in CRH-deficient mice.

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Cardiovascular Hormone Systems: From Molecular Mechanisms to Novel Therapeutics by Michael Bader


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