William J. McKenna, William T. Abraham, David Feldman's Current Opinion in Cardiology MAY 2009 PDF

By William J. McKenna, William T. Abraham, David Feldman

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Impact of arterial load and loading sequence on left ventricular tissue velocities in humans. J Am Coll Cardiol 2007; 50:1570–1577. Copyright © Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. 238 Cardiac failure 23 Kitzman DW, Higginbotham MB, Cobb FR, et al. Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: failure of the Frank-Starling mechanism. J Am Coll Cardiol 1991; 17:1065– 1072. 24 Sanderson JE, Fraser AG.

52 Wang J, Kurrelmeyer KM, Torre-Amione G, Nagueh SF. Systolic and diastolic dyssynchrony in patients with diastolic heart failure and the effect of medical therapy. J Am Coll Cardiol 2007; 49:88–96. 36 Brubaker PH, Joo KC, Stewart KP, et al. Chronotropic incompetence and its contribution to exercise intolerance in older heart failure patients. J Cardiopulm Rehabil 2006; 26:86–89. 53 Yu CM, Zhang Q, Yip GW, et al. Diastolic and systolic asynchrony in patients with diastolic heart failure: a common but ignored condition.

1%) for conventional cardiac causes (myocardial infarction, stroke or revascularization), leaving a full 67% of patients being readmitted for presumably noncardiac causes [27]. Among the 116 deaths, 70% were cardiovascular and 56% of these were not due to heart failure. This investigation conceptually defined heart failure as a clinical syndrome without including ejection fraction as the distinguishing criterion. It also underscores the challenge of identifying a population at sufficient risk for morbidity and mortality endpoints attributable to DHF and not comorbidities or ‘noncardiovascular causes’.

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Current Opinion in Cardiology MAY 2009 by William J. McKenna, William T. Abraham, David Feldman


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